Travellers arriving in the UK from dozens of countries no longer have to self-isolate for two weeks from Friday.
The rules are being relaxed for arrivals from more than 60 countries and British overseas territories.
However, Scotland still requires people from Spain and Serbia to quarantine – unlike England, Wales and Northern Ireland.
Foreign Office advice against taking a cruise holiday remains in place.
From Friday morning, people arriving in the UK from France, Italy, Belgium, Germany and dozens of other countries will no longer have to spend 14 days in quarantine .
But people who arrived from those countries at an earlier point in the last two weeks will still be expected to complete their period of isolation.
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Scotland, which from Friday has also made face coverings mandatory in shops, has said it will continue to quarantine passengers from countries with a higher prevalence of Covid-19 than its own.
It means people arriving in Scotland from Spain will still face quarantine rules. The Scottish government said data from the UK government shows the prevalence of the virus in Spain is 330 people per 100,000, compared with 28 people per 100,000 in Scotland.
First Minister Nicola Sturgeon said the “difficult decision” was necessary to protect Scotland from a resurgence of the virus and warned travellers not to try and bypass the restrictions by flying to airports in England.
The quarantine rules were introduced in June, with travellers asked to nominate an address where they would self-isolate, with fines of up to £1,000 for those who failed to comply.